Illumina Ventures is an independently managed, early-stage venture firm founded in 2016 and headquartered in Foster City, California, with an additional office in Dublin, Ireland. It operates in a strategic partnership with Illumina, which provides the majority of its capital and access to genomics expertise. The firm invests across the genomics and precision health ecosystem, with focus areas spanning life science tools (single-cell analysis, spatial biology, synthetic biology), diagnostics, therapeutics (cell and gene therapies, gene editing, AI-enabled drug discovery), digital health, and sustainability (agricultural biotech, biomanufacturing). It closed Fund I at $230M in 2017 and Fund II at $325M in late 2021; Fund III (Illumina Innovation Fund III) was originally targeted at $300M but was reduced to $200M amid challenging biotech fundraising conditions, with ~$60M raised as of late 2025. Check sizes range from $1M to $20M. The firm also operates Illumina Ventures Labs, an in-house company-creation engine providing capital, sequencing capacity, mentorship, and fully equipped genomics lab capabilities to early-stage startups. It typically syndicates with leading institutional and strategic investors. Founders can reach out via info@illuminaventures.com.
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