Impact Science Ventures

Impact Science Ventures is a San Francisco-based early-stage venture firm founded in 2021 investing $20-99M across pre-seed and seed stages in fundamental scientific breakthroughs solving the world's most pressing problems in energy, materials, semiconductors, biotech, and agriculture. The firm backs leading innovators creating paradigm-shifting advances in climate solutions, with four portfolio companies (Antora Energy, Brimstone, Fervo Energy, Twelve) recognized in TIME's Top 18 Greentech 2024. ISV's portfolio companies address hard-to-decarbonize sectors like cement, steel, and geothermal energy with breakthrough technologies demonstrating commercial viability and third-party verification. The firm combines deep science expertise with venture investing to accelerate translation of scientific breakthroughs into scalable climate solutions.