2048 Ventures

InvestorActive
Type: Venture FundStage: Pre-Seed, SeedLead: LeadsCheck: $500K–$3MFund Size: $82MSeries: Fund IIIFund Age: 0.7yLocation: NY, United StatesContinent: North AmericaWebsiteApply

2048 Ventures is a thesis-driven early-stage venture capital firm based in New York City and Boston. The firm leads Pre-Seed and Seed rounds with check sizes of $500K–$3M, targeting Vertical AI, Deep Tech, Healthcare, and Biotech startups. It operates a 'Pre-Seed Fast Track' program that can fund startups in as few as 10 business days for rounds of $500K–$1.5M. The firm has backed over 200 startups, including GlossGenius, Aerodome, TwoStep Therapeutics, Nomic, and Gorgias. In January 2026, 2048 Ventures closed its oversubscribed Fund III at $82M, its largest fund to date. The firm does not require warm introductions and reviews 100% of pitches submitted directly.

Deep Tech (Generalist)AI and Machine LearningBiotech, Life Sciences, Synthetic BiologyHealthcare and Med TechSoftware and SaaS

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