Asymmetric Capital Partners

Asymmetric Capital Partners is a Boston-based early-stage venture capital firm founded in 2021 by Rob Biederman, former co-founder and co-CEO of Catalant Technologies. The firm invests primarily at Pre-Seed through Series A in B2B technology companies, with a focus on three core areas: vertical software for legacy industries, Healthcare IT & Services, and SMB consolidations (rollups). Typical check sizes range from $2M to $10M as a lead investor, targeting approximately 20% ownership per deal. Fund I closed at $105M in October 2021 and backed 29 core investments; Fund II closed at $137M in October 2025, exceeding its $125M target. The team comprises former founders, operators, and PE investors who provide hands-on support across hiring, go-to-market, financial planning, and strategic advisory. LPs include family offices, institutional investors, and operator-founders. The firm does not publish a public application portal; founders can reach out via the website's contact form.